Embark
Study

A Clinical Research Study for Adults With Atopic Dermatitis

Go Beyond
the Surface
of Atopic Dermatitis

Atopic dermatitis is more than skin-deep—it’s a complex condition that affects people in many different ways. Researchers are exploring a potential treatment option to support those on this journey.
Discover more about the EMBARK Study.

You may be able to participate in the EMBARK Study if you:

Are at least
18 years old

Were diagnosed with atopic dermatitis (also known as eczema) and have had symptoms for at least 1 year

Haven't seen enough improvement from a previous or current atopic dermatitis treatment

If you are interested in participating, the study doctor or study team will review the additional study criteria with you.

All study-related care and study drugs (investigational drug or placebo) will be provided at no cost during participation. Participants may be reimbursed for travel and expenses.

About
Atopic Dermatitis

Atopic dermatitis, often known as eczema, is a chronic skin condition that affects many adults worldwide. Characterized by discolored, inflamed, and itchy skin, atopic dermatitis can significantly impact the quality of life and overall health of those affected.

Atopic dermatitis can be especially challenging due to its noticeable symptoms and discomfort, which can affect all areas of life. Through clinical research, we hope to better understand atopic dermatitis and find more treatment options for those affected. Learn more about this condition below.

Did You Know?

Eczema is a broad term that describes a group of conditions causing itchy, red, and inflamed skin and affects approximately 10% of people worldwide.1 Atopic dermatitis is the most common form of eczema. It typically starts in childhood and often continues into adulthood.

While atopic dermatitis is a chronic condition affected by both genetic and environmental factors, other types of eczema can be triggered by direct contact with irritants and have more immediate symptoms.1

Quick Facts

In people with atopic dermatitis, the skin’s barrier function is impaired. This weakened skin barrier allows moisture to easily escape, leaving the skin dry and dehydrated. It also makes the skin more vulnerable to irritants, allergens, and environmental factors that can trigger inflammation and symptoms.2,3
In 2006, researchers found that certain changes in the filaggrin gene can make people more likely to develop atopic dermatitis. The filaggrin gene provides instructions for making a protein that helps maintain the skin’s protective barrier.4
About 85% of people with atopic dermatitis describe itching as their most distressing symptom. It is also common to experience sore or painful skin and poor sleep caused by itching.2

Triggers and Environmental Factors5

Cleaning products:

Strong soaps and detergents

Allergens:

Dust mites, pet dander, pollen, certain foods

Climate:

Extreme changes in temperature and humidity

Certain materials:

Wool, polyester, latex

Stress:

Anxiety and stress are common triggers that can cause atopic dermatitis to flare up, which can result in a vicious cycle where the flare-up itself causes more stress.

Dry skin:

Moisturizers help repair and support the skin barrier, reducing the risk of flares and itching.
Sources:

1 “Eczema Stats.” National Eczema Association. January 27, 2025. https://nationaleczema.org/research/eczema-facts/

2 “Atopic Dermatitis.” National Eczema Association. January 27, 2025. https://nationaleczema.org/eczema/types-of-eczema/atopic-dermatitis/

3 “Atopic Dermatitis.” National Institute of Arthritis and Musculoskeletal and Skin Diseases. November 2022. https://www.niams.nih.gov/health-topics/atopic-dermatitis

4 “Revisiting the Roles of Filaggrin in Atopic Dermatitis.” Moosbrugger-Martinz, et al. May 10, 2022. https://pubmed.ncbi.nlm.nih.gov/35628125/

5 “Causes and Triggers of Eczema.” National Eczema Association. January 27, 2025. https://nationaleczema.org/eczema/causes-and-triggers-of-eczema/

Atopic dermatitis can significantly affect daily life, but we can impact the future of atopic dermatitis management through clinical research.

Doctors and researchers are working tirelessly to find treatment options to help those living with atopic dermatitis. Learn more about research aiming to help manage atopic dermatitis and its symptoms and see if the EMBARK Study is right for you.

Embark
Study

Consider joining the
EMBARK Study today.
© 2025 Clinical Trial Media. All Rights Reserved. The images depicted contain models and are being used for illustrative purposes only.